Senior Project Leader Medicinal Chemistry

As Senior Project Leader in Medicinal Chemistry, you will be managing the design and execution of medicinal chemistry programs as well as the CMC activities related to the clinical candidates.

 

YOUR BACKGROUND

  • Ph.D. in Organic/Medicinal Chemistry with a minimum of 10 years of relevant scientific experience in the pharmaceutical industry
  • Proven track record of project leadership in all aspects of the drug discovery process, from target discovery through to early clinical development
  • Strong communication, problem-solving and analytical skills
  • Enthusiasm for working in an interdisciplinary environment
  • Relevant chemical-pharmaceutical development and/or CMC management experience with strong understanding of cGMP and regulatory requirements
  • Able to work under pressure
  • English proficiency is a must

 

KEY RESPONSIBILITIES

  • Design and execution of medicinal chemistry research projects from initial hit finding stages and exploratory chemistry, through lead optimization, to the identification of high-quality drug candidates for clinical development
  • Active collaboration with other cross-functional groups of the company for integrating aspects of the entire drug discovery value chain, incorporating data and concepts from biochemistry, cell biology, biophysical methods, structure-based drug design, ADME/PK, pharmacology and toxicology
  • Management of external chemists and collaborations to solve synthetic problems, maximizing efficiency and expediting the invention of novel molecules
  • Collaboration in the CMC activities related to drug substance development/manufacturing and the preparation of related reports for IND/IMPD or NDA/MAA submissions

 

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